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Patients considering medically supervised weight loss should be aware of these restrictions: Section 503A pharmacies: Enforcement began April 22, 2025 Section 503B facilities: Must cease by May 22, 2025 Continued compounding may result in FDA enforcement actions Limited exceptions exist for documented allergies or specific medical needs Important Safety Note: The FDA strongly advises against using compounded semaglutide when FDA-approved alternatives are available

That year, an estimated 8.2 million prescriptions for it were written in the U.S., more than quadruple the number just two years earlier