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This mechanism represents a control of the influx of fatty acyl units into mitochondria in response to the intra-mitochondrial acetyl-CoA level, in addition to the finely regulated mechanism of CPT1 by malonyl-CoA
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Animal studies have also found that intermittent fasting lowers IGF-1 more effectively than long-term calorie restriction, but other studies have found no difference between the two (32, 33)
