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Short-acting GLP-1RAs exhibit a considerable fluctuation in circulating levels during the daytime that, in turn, produce an intermittent activation of GLP-1R, resulting in different pharmacodynamic effects compared to long-acting GLP-1RA (66)
J Pediatr Endocrinol Metab 2014;27((1-2)):23-29
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The liver uses glutathione to conjugate these toxins, making them water-soluble so they can be excreted
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