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For energy and focus, most notice an effect within 14 weeks

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Hippocampus, Purkinje cells, amygdala, substantia nigra, striatum, and several areas of the thalamus, hypothalamus, and brainstem are all positive for GIP mRNA and/or protein [19, 20, 24]

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doi: 10.1152/physrev.2000.80.1.135 Hypertension

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This review covers the molecular identity and central nervous system distribution of the GLP-1 receptor, the mechanisms proposed to underlie its neuroprotective effects, and the clinical trial record in Parkinsons and Alzheimers disease

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