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Many peptide systems discussed herein have been repeatedly shown to exert robust physiological effects in vivo , often across multiple species, yet lack approved therapeutic analogs or advanced clinical programs despite decades of investigation

Reasons patients give for stopping include reaching a plateau in weight loss, inability to tolerate side effects, or even inability to get the medication due to shortages

And the third included those without enough supporting information for the FDA to make an informed decision and therefore wouldnt be used for compounding

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