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Funding No funding was received to assist with the preparation of this manuscript

It is the clearest clinical example of the glucagon paradox because it incorporates glucagon receptor activation into a molecule that has produced very large reductions in body weight

[3] [8] Regular follow-up appointments allow monitoring of symptom patterns and treatment response, ensuring that Zepbound therapy remains both safe and effective for individual patients

Although a causal relationship between alterations in the composition of the gut microbiome and AD symptoms is not clear, the modulation of gut microbiota by oral or topical skin probiotics was shown to ameliorate AD, thus providing new ideas for probiotic intervention strategies against AD in the future