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Diabetes Care 38 , 10161029 (2015)

B12/MIC supports weight loss by boosting energy, enhancing fat metabolism, and helping the body convert fat into usable fuel

These results showed that TG-induced ER stress triggered nuclear translation of NF-B, contributing to pro-inflammatory cytokine transcription and subsequently promoting an ECM catabolic process

The bottom line: Our findings suggest that GLP-1RA and SGLT2i (and especially SGLT2i with the lowest number needed to treat (NNT) for nearly all study outcomes) may be the preferred glucose-lowering agents for cardiovascular risk reduction in patients at moderate risk for CVD, building on and consistent with existing RCT evidence in the high-risk population. This report highlights potential preference for GLP-1 drugs as a first-line treatment for Type 2 diabetes related to its cardioprotective effect