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We can make educated guesses by looking at existing Novo Nordisk medications

The finding that GLP-1(936) acts by reducing the number of docked granules provides a simple and unifying explanation for its capacity to inhibit glucagon secretion regardless of whether it is evoked by low glucose, membrane depolarisation or a -adrenergic agonist

This is noteworthy as (1) many biologically active peptides contain an -helix (a large fraction of PPIs involve an -helix) and (2) those helix portions could potentially be replaced or partially replaced by oligoureas with minimal effect on the binding while improving the proteolytic resistance of the peptide

Are Glutathione capsules effective