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The safety profile of exenatide and other GLP-1 receptor agonists has been extensively evaluated through clinical trials and post-marketing surveillance
Finding clear answers is not always easy
Date: February 11, 2026 Source: Cochrane Summary: Three major reviews commissioned by the World Health Organization find that GLP-1 drugs including tirzepatide (sold as Mounjaro and Zepbound), semaglutide (Ozempic and Wegovy), and liraglutide (Victoza and Saxenda) can lead to substantial weight loss in people with obesity
This increase could be blunted by treatment with an antibiotic that binds to LPS (polymyxin B) or by a TLR4 antagonist (TAK-242)
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