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FIGURE 1 Glucagon-Like Peptide-1 Receptor/Mitogen-Activated Protein Kinase Signal Pathway Mitogen-activated protein kinase (MAPK) belongs to silk/threonine protein kinase, mainly including extracellular signal-regulated kinase (Erk1/2), Jun N-terminal kinase (JNK) subfamily, p38 mitogen-activated protein kinase and ERK5 ( via GLP-1R (Figure 1)

Intermenstrual or postcoital bleeding: Bleeding between periods or after sexual intercourse always requires investigation to exclude cervical pathology or other gynaecological conditions