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The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Physically active individuals often generate increased oxidative stress through repetitive muscle contraction, tissue microtrauma, and elevated metabolic demand
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This finding does not establish causality, but it is consistent with a model in which robust mitochondrial peptide signaling is a feature of successful aging rather than a peripheral correlate
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