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Aug 2013;4(8):902-910

Key Therapies to Watch - Tirzepatide (GLP-1/GIP): Superior weight loss and A1C reduction - Retatrutide (GLP-1/GIP/glucagon): Under investigation for obesity, NASH, and cardiometabolic risk - Semaglutide (GLP-1 only): Approved for obesity and diabetes Open Question How are you preparing to integrate dual and triple agonist therapies into your obesity care pathways and what strategies help patients understand their hormonal hunger signals

Table of Contents Signs That Retatrutide May Be Working Key early signs include reduced appetite, gradual weight loss beginning within four to eight weeks, and improved fasting blood glucose or HbA1c in people with type 2 diabetes or insulin resistance

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