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Compounded Reality The Endocrine Society's 2015 clinical practice guideline on menopausal hormone therapy states: "We recommend against the use of custom-compounded hormones, since there are no data showing they are safer than or superior to FDA-approved menopausal HT preparations." (Endocrine Society guideline) That position has not changed in subsequent updates
It's what the research consistently shows
They are often used alongside healthy lifestyle habits to improve overall metabolic function
Moderate, regular exercise supports treatment outcomes better than extreme regimens
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