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While randomized controlled trials offer rigorous evidence, they may not fully represent older, multimorbid, or polytreated patients seen in primary care
Clinical data shows that patients typically experience meaningful results within the first month, though individual timelines vary based on starting weight, metabolism, and adherence
Lee WC, Gomez DR, Ahang J, Jalali A, Roh W, Reuben A, Lu W, Chow CW, Wu CC, Fujimoto J, Antonoff M, Moran C, Sulman EP, Rao G, Swisher SG , Heymach J, Wistuba II, Futreal A, Zhang J
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