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There are specific scenarios where combining these two forms of B12 might be considered, as part of a tailored treatment plan: Reducing Injection Frequency: For some individuals who require lifelong B12 due to malabsorption but dislike frequent injections, a doctor might explore if high-dose oral supplements can help maintain adequate levels between less frequent injections

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If someone comes in feeling chronically tired or foggy and cant figure out why, B12 is one of the first things we look at." Dr

These side effects are significantly more common when dosing is above physiological levels