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For instance, interferon- (IFN-) released by cytotoxic T cells (CTLs) activates the downstream JAK-STAT1 signaling pathway, downregulating the expression of the cystine/glutamate antiporter system (xc system), thereby reducing intracellular GSH synthesis, increasing free iron levels, and ultimately inducing ferroptosis in GBM cells [91]

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Centrifugation was performed for 10 minutes at 12,000 rev/min and 4 C

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Of particular interest is silymarin, a derivation of the milk thistle plant

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The Importance of a Holistic Approach Increasing glutathione levels is not just about incorporating specific foods or supplements

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