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This is the primary source for PK of the non-DAC modified version and explains why it is dosed daily rather than weekly
Unlike other approved GLP-1 medications, Wegovy and Zepbound, which also target the gut hormone GLP-1, retatrutide targets three receptors known to regulate appetiteGLP-1, glucagon and glucose-dependent insulinotropic polypeptide (GIP)
Chen Xin Yi C, Wu LY, et al
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