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Increasing evidence points to oxidative stress, mediated by free radicals such as ROS and RNS, as a critical factor in the pathogenesis of these diseases [40]
Patients may experience headache or cold symptoms, such as sore throat, runny nose, and congestion
Potential neuroprotective PD therapies and clinical trials are now targeting specific PD subtypes based on genetic markers causing or increasing the disease risk, such as therapies targeting LRRK2 , GBA1 and alpha-synuclein (Sardi et al., 2018)
Positive screens proceed to confirmation testing with even more specific methods
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