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However, it is important to note that erythrocytes generate ROS primarily as a result of (i) hemoglobin oxidation, which can be considered as an iron-mediated Fenton reaction, (ii) the activity of NAPDH oxidase and (iii) xanthine oxidoreductase, while in nucleated cells ROS are mainly generated in the mitochondrial electron transport chain

Patients undergoing cancer treatment should consult their oncologist before using glutathione supplements or medications

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People with Malabsorption Disorders : Conditions like celiac disease or Crohns disease can hinder vitamin B12 absorption