Pharmacol Res 117:218227 Rivetti S, Romano A, Mastrangelo S, Attin G, Maurizi P, Ruggiero A (2023) Aminoglycosides-related ototoxicity: mechanisms, risk factors, and prevention in pediatric patients
Both therapies have been proven to be safe, with no known side effects
This is supported by a 12 rotation of the LBD layer in open GluK2 versus GluA2 (Gangwar et al., 2024b)
A better understanding of the detailed interactions between the factors involved will contribute to further elucidate the cell defense capability, which is impaired in neurodegenerative diseases such as ALS [67, 141, 170], and may reveal the path for identifying novel potential therapeutic targets