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Physiology, Synapse

Chronic Illness Management 5.4.3.3.8

While TAC values showed significant gradual increase and reached the highest values at 168 h (2.75 0.58 mM/l) after LC administration, compared to 0 h (1.12 0.05 mM/l)

Daily formulations include: Rybelsus (oral semaglutide) Saxenda (liraglutide) Victoza (liraglutide) Adlyxin (lixisenatide) Byetta (exenatide, twice daily) Weekly formulations include: Ozempic (semaglutide) Wegovy (semaglutide) Trulicity (dulaglutide) Mounjaro (tirzepatide) Zepbound (tirzepatide) Bydureon (extended-release exenatide) Longer-acting agents achieve sustained receptor activation through structural modifications such as albumin binding or Fc-fragment fusion, which extend half-life and allow once-weekly dosing