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In other words, glucagon counteracts insulin and worsens diabetes, so blocking its secretion helps with disease management.9 Slows gastric emptying Increases satiety On top of decreasing your appetite outside of meal times, a GLP-1 RA increases your feeling of fullness when you do eat.12 Again, the result is that youre less likely to take in more calories throughout the day than you expend

This speaks to nothing of clinical relevance in human patients merely a theoretical mechanism

John Myers, the original, pioneered since the late 50's

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