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A compound that is clean enough for a binding assay is not automatically clean enough for a quantitative cell-based readout where a co-eluting impurity could carry activity of its own
Sakata, Y
"This all appears to be a good news story," said Susan Jebb, a public health nutrition scientist at Oxford University and co-author of a new BMJ study
(1) Neurodevelopmental Homeostasis: In the healthy state, mitochondrial oxidative phosphorylation (Complexes IV) supports efficient ATP generation, redox stability, and formate flux from the mitochondrial folate cycle (via SHMT2, MTHFD2)
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