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If you cannot commit to the discipline of twice-weekly injections with precise measurements, standard weekly dosing is safer
Significant weight loss from tirzepatide may reduce levothyroxine requirements in some patients, necessitating TSH monitoring at baseline, after substantial weight loss, and every 6-12 months once stable
GLP-1RA might also be valuable in knee osteoarthritis (KOA) amelioration, which represents the typical load-bearing complication of obesity and a leading cause of disability and reduced health-related quality of life
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