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Other flagged risks include: Pancreatitis Gallbladder disease Possible worsening of diabetic retinopathy in people with diabetes Rare reports of suicidal thoughts Rodent studies showed an increased risk of medullary thyroid tumors, so semaglutide is contraindicated for people with a personal or family history of medullary thyroid carcinoma or MEN2 syndrome

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Improved Metabolic Health Studies suggest semaglutide and Tirzepatide can both improve overall metabolic health by reducing inflammation and potentially lowering bad cholesterol (LDL) levels

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