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Based on these findings, it was hypothesized that a secreted metabolite that upregulates BAs might be responsible for the observed effects
During phase 1 trials in NASH patients, efocipegtrutide showed a half-life of around 5.9 days, and was capable of reducing body weight by 5.1% when administered weekly at 0.08mg/kg, after 12 weeks [36]
FOR LOWER BLOOD PRESSURE SOURCE: National Library of Medicine
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