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This study represents one of the largest metabolomic studies of a clinical cohort

The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool

It shows up as dormant hair follicles that stop receiving the growth signals they once did

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