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Together, these studies highlight the complex interplay between CKD, neuroinflammation, and gut-derived signals, providing strong evidence that the gut microbiota and its metabolites play a significant role in promoting neuroinflammatory processes in CKD, which in turn contribute to cognitive decline and neurodegenerative changes

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Guerrant RL, Steiner TS, Lima AA, Bobak DA (1999) How intestinal bacteria cause disease

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It is a small protein molecule that your body produces on its own to repair tissue, regulate inflammation, and signal healthy cell activity

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