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Since the FDA approved Ozempic in 2017, the drugs manufacturer, Novo Nordisk, has not included warnings that the medication can cause gastroparesis in its prescription information
To determine whether this variant is likely to be causal, we considered all 42 variants within the 99% credible set of the association, and annotated by predicted functional consequence (Supplementary Table 9)
As illustrated above, our algorithm for product innovation focuses on identifying indications that have an unmet medical need, have a clinically validated parent drug or pathway, are suitable to our TransCon technologies, have potential for creating a clearly differentiated product, have a potential established development pathway, and have the potential to address a large market