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[18] [19] For weight management, good candidates include adults with obesity (BMI 30 kg/m) or those who are overweight (BMI 27 kg/m) with weight-related health complications

In the first phase of the current study, SR18, docked to GLP-1R, was subjected to 1 s MD simulations to directly compare its agonist-like properties with the established agonists and antagonists of GLP-1R reported earlier

On 23 dpi, Satb2 expression declined from approximately 85% in the physiological state to about 40%, reaching around 95% by 5 dpi, and returning to baseline levels (approximately 90%) by 7 dpi (Fig