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The assay was designed to demonstrate the biochemical activity of c-met binding sites including Y198 and Y250 (in K1 and K2 domains of HGF, respectively) by significant changes in optical absorbance (expressed as relative unit) within a range from a baseline level (a negative control without HGF

only two studies are from Japan and one study is from the AsiaPacific region

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For context on topical evidence vs systemic claims, stability, and COA limitations, see the GHKCu hub