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No head-to-head trial exists comparing monotherapy versus the stack on any clinical outcome

Chronic mitochondrial inefficiency is an established source of continuous reactive oxygen species generation and can further compromise GSH synthesis and regeneration through effects on ATP production and the -glutamyl cycle [38]

10.1016/j.avsg.2017.06.131 Ann Vasc Surg

J Allergy Clin Immunol 127(6):14861493e2 Buescher PA, Whitmire JT, Plescia M (2008) Relationship between body mass index and medical care expenditures for North Carolina adolescents enrolled in medicaid in 2004