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Description

Eur J Endocrinol

Take 15-30 minutes before training with a source of carbohydrates (fruit, juice, or a carb-containing meal) for optimal muscle carnitine uptake

Lipid peroxidation preferentially accumulates at lysosomal membranes and precedes lysosome rupture, transcription factor EB (TFEB) activation, and cathepsin-dependent plasma membrane breakdown, thereby positioning lysosomal stress at the center of population-scale death amplification

Patients with obesity, particularly when affected by cardiovascular and renal comorbidities in the context of CKM, may represent an ideal target population