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Moreover, rats treated with 1% neohesperidin dihydrochalcone for 1 month showed reduced amygdala neuroinflammation via suppression of cAMP/PKA pathway activity, restoration of cortical 5-HT, DA, and NE levels, and reversal of anxiety- and depression-like behaviors (Jiang et al., 2023)

IPE is a mixture of inulin (a natural substance found in chicory and onions) and propionate (a naturally occurring short-chain fatty acid)

However, the factors that trigger these transcriptional changes during intracellular infection have not yet been resolved

In the lung cell cultures, the peptide complex apparently reduced edema, inflammatory cell infiltration, and overall histologic injury scores