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The critical question lies in determining whether elevated circulating metabolite concentrations represent disease-driving factors or secondary manifestations of excretory dysfunction
doi:10.1515/acph-2016-0043 Zhou K, Zhao R, Geng Z, et al
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Uterine fibroids are detected by ultrasound, while diagnosing PCOS relies on identifying a cluster of symptoms often subjectively and using inconsistent thresholds through clinical examination, ultrasound and endocrine biomarkers, many of which are inaccessible in low-resource settings
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