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This class of polyphenols have a lower redox potential than oxygen and superoxide radicals, making these antioxidants better suited to bind active oxygen (Duthie and Crozier, 2000)

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Dose Range: 200600 mcg daily with gradual titration

The review also documented GSHs role in regenerating vitamin E following detoxification of lipid peroxyl radicals, its involvement in the glyoxalase systems detoxification of dicarbonyl stress induced by methylglyoxal and glyoxal, and its regulation of redox signalling through reversible S-glutathionylation of critical protein cysteine residues