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Increases Collagen Production: It may improve collagen synthesis, which is essential for maintaining the structure of connective tissues, skin, and joints
However, if the biological macromolecules have been denatured or experienced significant stress, the intended medicinal effects can become compromised
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Additionally, metformin has been utilized for alleviating OA symptoms through various mechanisms, including anti-inflammation, activation of autophagy, inhibition of osteoclast activation, and regulation of chondrocyte aging 21,22,23,24
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