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Gastrointestinal symptoms such as mild digestive discomfort affect some patients, though severe reactions are uncommon
Traditional obesity intervention strategies (e.g., dietary control, exercise, conventional weightloss drugs) are often limited by slow onset, obvious side effects, and high rebound rates, and can hardly fundamentally reverse the abnormal metabolic phenotype of adipose tissue
They exist because B12 stores need rebuilding before a maintenance rhythm makes sense
Usually, B12 is absorbed once it is attached to the protein intrinsic factor (IF), made by cells in the stomach
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