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Think of these as three possible routes estrogen can take on its way out of your body

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10.3892/or.2016.4951 25 ChenX.ZhangJ.RuanW.HuangM.WangC.WangH.et al (2020)

Overexpression of the histone dimethyltransferase G9a in nucleus accumbens shell increases cocaine self-administration, stress-induced reinstatement, and anxiety