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We assessed L-methionine, L-homocysteine, L-cysteine, L-glutathione, and L-taurine supplementation in dys-1(eg33) thrashing ability (an established indirect measure of muscle health and animal healthspan), to determine effective health-preserving concentrations for each SAA (Fig

doi: 10.1016/j.cell.2021.07.001

Furthermore, we have shown that the GSK3-mediated BACE1 gene expression is dependent on NF-B signaling, and that inhibition of GSK3 can decrease BACE1 expression and reduce Alzheimer-associated phenotypes [236]