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John Eng at the VA Medical Center in the Bronx discovered exendin-4, a peptide in Gila monster venom that mimicked GLP-1 but lasted hours instead of minutes

It covers amino acid sequences, molecular weight, conformational differences, melanocortin receptor binding profiles, and analytical methods for purity verification

Ethics declarations Ethics approval and consent to participate Animal studies and procedures were carried out in accordance with an approved protocol from the Institutional Animal Care and Use Committee (IACUC) at the Fourth Military Medical University (IACUC-20220505)

Helps reduce the appearance of fine lines and wrinkles