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MOTS-c: The cellular energy optimizer MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a mitochondrial-derived peptide produced from DNA inside the mitochondria that helps regulate energy and improve metabolic homeostasis at the cellular level
This self-perpetuating loop drains the cells glutathione reserves, as the antioxidant is rapidly consumed in a desperate attempt to neutralize the surging ROS
PCA analyses showed natural separation between the two groups with some overlap observed in the scores (Fig
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