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Where GLP-1 agonists like semaglutide work primarily through incretin-based signaling, cagrilintide approaches satiety from a completely different neurological pathway
When the EMA announced its review, there had been 28 reports of the suicidal and self-injurious behaviour associated with semaglutide and 23 reports with liraglutide, as documented in the MHRA Yellow Card reporting scheme