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Cellular GSH acts as a cytoprotective species via (i) its ability to provide thiol reducing equivalents in metabolic reactions and preserve a millimolar-scale reduced-thiol cytoplasmic milieu

The most dramatic glutathione before and after transformations tend to happen when the treatment is paired with daily sun protection and a healthy lifestyle, since UV exposure is the single biggest driver of new pigmentation

In other words, the body did not release GH as a perfectly flat hormonal signal but retained a degree of physiological pulsatile secretion