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[27] The connection between GSTP inhibition of the pro-apoptotic JNK pathway and the isozyme's overexpression in drug-resistant tumor cells may itself account for the tumor cells' ability to escape apoptosis mediated by drugs that are not substrates of GSTP

Immune support Glutathione contributes to normal white-blood-cell function, so there is a plausible mechanistic link to immune support, and patients frequently seek it for that reason