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Acknowledgements This work was supported by grants from the NIH (NIAAAR01 AA017442, Z.S.), the Natural Science Foundation of China (81470845, Z.S

otherwise GLOW covers the same regenerative components

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The gut microbiota may be interacting with the other pathways such as inflammation, or endocrine which then interact with and affect the integrity of the BBB, but either way it is now apparent that the gut microbiota is a modulator of BBB integrity