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2.4 Switching to SEMGLEE from Other Insulin Therapies Dosage adjustments are recommended to lower the risk of hypoglycemia when switching patients to SEMGLEE from other insulin therapies [see Warnings and Precautions (5.3)].When switching from: Once-daily insulin glargine 300 units/mL to once-daily SEMGLEE (100 units/mL), the recommended starting SEMGLEE dosage is 80% of the insulin glargine, 300 units/mL dosage that is being discontinued
Discontinuation rates due to adverse effects were also higher with retatrutide being 16-17% compared with 2% with dulaglutide and 0-4% with placebo
But some 2,000 state employees who have access to GLP-1s through their health insurance will lose that coverage soon, at the order of the Department of Administrative Services
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