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For instance, in transgenic AD animal models, Lipid Nanoparticles have been employed to deliver siRNA that targets the amyloid precursor protein (APP) or presenilin 1 (PSEN1)
especially when you consider the long-term nature of these types of treatments
This recommendation was based primarily on preventing hypotension (low blood pressure), and secondarily, on preventing the fishy body odor due to increased excretion of trimethylamine
effects probably related to its anti-diabetic and weight-lowering properties
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