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Too much growth hormone can cause side effects including joint pain, water retention, and carpal tunnel-like symptoms
If patients respond well and experience minimal side effects, the dose can be increased to 50 mg twice daily or adjusted further as clinically appropriate
Given the benefits of this class of medication, it is likely more approvals for more indications will be on the horizon
This phase II clinical trial provided some evidence of benefit on decline in the ALSFRS-R and used a combination of agents to tackle several pathophysiological disease mechanisms
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