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PTPN22 (short for protein tyrosine phosphatase non-receptor type 22), known as a risk factor in multiple autoimmune disorders, reduces T-cell activity by removing phosphate groups from phosphorylated proteins such as LCK, Fyn, and Zap70, which are associated with T-cell receptor signaling pathway
Care 45 , 27532786 (2022)
This is particularly crucial when normal glucose metabolism is impaired, a phenomenon frequently observed in neuroinflammatory conditions
As an nsMRA, finerenone does not appear to cause gynecomastia
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